Facial Papules and Intestinal Lipomatosis

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[Asymptomatic facial papules].

Biopsy was performed of one of the lesions: in the superficial dermis, beneath a normal epidermis, there was a diffuse proliferation of histiocytic cells with clear, foamy cytoplasm; in some areas Touton giant cells could be identified (Figure 2). There was also a moderate degree of vascular proliferation. Immunohistochemistry was positive for S100, CD68, and for CD34 (in the vessels) and was n...

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SkIndia Quiz 29: Multiple facial papules

Department of Skin and VD, Topiwala National Medical College and BYL Nair Hospital, Mumbai, Maharashtra, India A 40-year-old woman presented with gradual onset of multiple raised skin-colored lesions over face since two months. There was no history of any associated complaints such as burning, itching, or pain. There was no history of antecedent trauma, seasonal variation, systemic ailments, or...

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PIK3CA activating mutations in facial infiltrating lipomatosis.

BACKGROUND Facial infiltrating lipomatosis is a nonheritable disorder characterized by hemifacial soft-tissue and skeletal overgrowth, precocious dental development, macrodontia, hemimacroglossia, and mucosal neuromas. The authors tested the hypothesis that this condition is caused by a somatic mutation in the phosphatidylinositide-3 kinase (PI3K) signaling pathway, which has been indicted in o...

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Diffuse Intestinal Lipomatosis Presenting as Adult Intussusception

Background: A 25-year old female presented to the Emergency Department with intermittent abdominal pain. Computed tomography imaging demonstrated multiple fat-density tumors in the small intestine and colon associated with two long-segment intussusceptions. Methods: Colonoscopy showed a partially obstructing multilobulated mass in the descending colon; biopsy was non-diagnostic. At exploratory ...

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Large Forehead Nodule with Multiple Facial and Oral Papules.

Answer: B A 25-year-old male presented with an asymptomatic nodule on his forehead. It first appeared 2 years ago and gradually enlarged with time. Physical examination revealed a 13 mm x 15 mm smooth solitary skin-coloured nodule on his forehead (Fig. 1a). He also had several skin-coloured papules on his nose and over his left periocular region (Fig. 1b), oral papillomatosis on his tongue (Fig...

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ژورنال

عنوان ژورنال: Actas Dermo-Sifiliográficas (English Edition)

سال: 2010

ISSN: 1578-2190

DOI: 10.1016/s1578-2190(10)70840-4